Palmitoylethanolamide No Further a Mystery
Central administration of palmitoylethanolamide cuts down hyperalgesia in mice by using inhibition of NF‐κB nuclear signalling in dorsal root ganglia. Eur J PharmacolCosta and colleagues [178] have proposed that PEA was in a position to lower mechanical allodynia and thermal hyperalgesia pursuing sciatic nerve constriction in mice, by way of an